4Life Transfer Factor Plus®: What's Inside — and Why It's the Best Seller

The best-selling product in this store, ingredient by ingredient — so you know exactly what you're taking and why.

The one-line summary

4Life Transfer Factor Plus® is the Tri-Factor® peptide formula plus a botanical and mushroom blend called Cordyvant™. It has been 4Life's flagship for over two decades, and it is the product our customers reorder more than any other.

Part one: the Tri-Factor® Formula

The foundation is the same peptide blend found in Transfer Factor® Tri-Factor®:

• UltraFactor® — transfer factor peptides concentrated from cow colostrum*
• OvoFactor® — complementary peptides from chicken egg yolk*
• NanoFactor® — a concentrate of immune-modulating molecules*

Together these support what 4Life calls the 4R model — helping your immune system recognize, respond, remember, and repair.* The full science story is on our Immune Science page.

Part two: the Cordyvant™ blend

This is what separates Plus from everything else in the line — a blend of traditional immune-supporting ingredients:*

• Maitake and shiitake mushrooms — mushrooms long used in wellness traditions, standardized for consistency*
• Cordyceps — the namesake of the blend*
• Beta-glucans (from baker's yeast and oat) — well-studied polysaccharides*
• Inositol hexaphosphate (IP-6), agaricus, olive leaf extract, and zinc — rounding out the formula*

Who Plus fits best

Plus is our default recommendation for first-time customers who want one comprehensive daily product, and it's the formula long-time 4Life customers tend to stay on. It's a two-capsule daily serving, vegetarian capsules, made in the USA. If you're comparing it against the newer Max formula — broader peptide sources, more capsules, higher price — the full side-by-side is here: Plus vs Max.

Common questions

Is Plus stronger than regular Tri-Factor®?

Plus contains everything Tri-Factor® does, with the Cordyvant™ blend added. If you want just the peptides, Tri-Factor® is the simpler choice; if you want the botanicals too, Plus is the more comprehensive one.*

Does it contain allergens?

The peptides derive from dairy colostrum and egg yolk, and the blend includes oat and yeast — see our side effects & safety guide and always check the current label.

How should I take it?

Two capsules daily with water — with food if you have a sensitive stomach. Consistency over months matters more than timing.*

Where to get it

Order Transfer Factor Plus® here with free U.S. shipping, we cover your sales tax, and same-day fulfillment on business-day orders before 2 PM ET — backed by our 30-day money-back guarantee.

About this article: Written and maintained by Kevin Moore, owner of 4LifeTransferFactorProducts.com and an independent 4Life Affiliate. Ingredient information reflects 4Life Research's published label; check the current label for the definitive list. Last reviewed: August 2026.

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.